MERS epidemiological investigation to detect potential mode of transmission in the 178th MERS confirmed case in Pyeongtaek, Korea
Identifieur interne : 001709 ( Main/Exploration ); précédent : 001708; suivant : 001710MERS epidemiological investigation to detect potential mode of transmission in the 178th MERS confirmed case in Pyeongtaek, Korea
Auteurs : Kyujin Chang [Corée du Sud] ; Moran Ki [Corée du Sud] ; Eun Gyu Lee [Corée du Sud] ; Soon Young Lee [Corée du Sud] ; Byoungin Yoo [Corée du Sud] ; Jong Hyuk Choi [Corée du Sud]Source :
- Epidemiology and Health [ 2092-7193 ] ; 2015.
Abstract
Most cases of Middle East Respiratory Syndrome (MERS) infection in Korea (outbreak: May 11-July 4, 2015) occurred in hospital settings, with uncertain transmission modes in some cases. We performed an in-depth investigation epidemiological survey on the 178th case to determine the precise mode of transmission. A 29- year-old man living in Pyeongtaek presented on June 16 with a febrile sensation, chills, and myalgia. Upon confirmatory diagnosis on June 23, he was treated in an isolation room and discharged on July 2 after cure. An epidemiological investigation of all possible infection routes indicated two likely modes of transmission: exposure to MERS in Pyeongtaek St. Mary’s Hospital during a visit to his hospitalized father (May 18-29), and infection through frequent contact with his father between the latter’s referral to Pyeongtaek Good Samaritan Bagae Hospital for treatment without confirmatory diagnosis until his death (May 29-June 6). Although lack of clear proof or evidence to the contrary does not allow a definitive conclusion, all other possibilities could be excluded by epidemiological inferences. While it is impossible to trace back the modes of transmission of all cases in a large-scale outbreak, case-by-case tracking and isolation of infected individuals and those in close contact with them is important in preventing the spread. Efforts should be made to establish a methodology for rapid tracking of all possible contacts and elimination-based identification of the precise modes of transmission.
Url:
DOI: 10.4178/epih/e2015036
PubMed: 26493651
PubMed Central: 4591909
Affiliations:
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We performed an in-depth investigation epidemiological survey on the 178th case to determine the precise mode of transmission. A 29- year-old man living in Pyeongtaek presented on June 16 with a febrile sensation, chills, and myalgia. Upon confirmatory diagnosis on June 23, he was treated in an isolation room and discharged on July 2 after cure. An epidemiological investigation of all possible infection routes indicated two likely modes of transmission: exposure to MERS in Pyeongtaek St. Mary’s Hospital during a visit to his hospitalized father (May 18-29), and infection through frequent contact with his father between the latter’s referral to Pyeongtaek Good Samaritan Bagae Hospital for treatment without confirmatory diagnosis until his death (May 29-June 6). Although lack of clear proof or evidence to the contrary does not allow a definitive conclusion, all other possibilities could be excluded by epidemiological inferences. While it is impossible to trace back the modes of transmission of all cases in a large-scale outbreak, case-by-case tracking and isolation of infected individuals and those in close contact with them is important in preventing the spread. Efforts should be made to establish a methodology for rapid tracking of all possible contacts and elimination-based identification of the precise modes of transmission.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Moran, Ki" uniqKey="Moran K">Ki Moran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zumla, A" uniqKey="Zumla A">A Zumla</name></author><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name></author><author><name sortKey="Perman, S" uniqKey="Perman S">S Perman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choi, Jw" uniqKey="Choi J">JW Choi</name></author><author><name sortKey="Kim, Kh" uniqKey="Kim K">KH Kim</name></author><author><name sortKey="Cho, Ym" uniqKey="Cho Y">YM Cho</name></author><author><name sortKey="Kim, Sh" uniqKey="Kim S">SH Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name></author><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abroug, F" uniqKey="Abroug F">F Abroug</name></author><author><name sortKey="Slim, A" uniqKey="Slim A">A Slim</name></author><author><name sortKey="Ouanes Besbes, L" uniqKey="Ouanes Besbes L">L Ouanes-Besbes</name></author><author><name sortKey="Hadj Kacem, Ma" uniqKey="Hadj Kacem M">MA Hadj Kacem</name></author><author><name sortKey="Dachraoui, F" uniqKey="Dachraoui F">F Dachraoui</name></author><author><name sortKey="Ouanes, I" uniqKey="Ouanes I">I Ouanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name></author><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Corée du Sud</li></country></list><tree><country name="Corée du Sud"><noRegion><name sortKey="Chang, Kyujin" sort="Chang, Kyujin" uniqKey="Chang K" first="Kyujin" last="Chang">Kyujin Chang</name></noRegion><name sortKey="Choi, Jong Hyuk" sort="Choi, Jong Hyuk" uniqKey="Choi J" first="Jong Hyuk" last="Choi">Jong Hyuk Choi</name><name sortKey="Ki, Moran" sort="Ki, Moran" uniqKey="Ki M" first="Moran" last="Ki">Moran Ki</name><name sortKey="Lee, Eun Gyu" sort="Lee, Eun Gyu" uniqKey="Lee E" first="Eun Gyu" last="Lee">Eun Gyu Lee</name><name sortKey="Lee, Soon Young" sort="Lee, Soon Young" uniqKey="Lee S" first="Soon Young" last="Lee">Soon Young Lee</name><name sortKey="Yoo, Byoungin" sort="Yoo, Byoungin" uniqKey="Yoo B" first="Byoungin" last="Yoo">Byoungin Yoo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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